HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Prolinol → HCID 42629810, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Prolinol | HCID 640091 | — |
| Reactant | 6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester | HCID 66599292 | — |
| Product | HCID 42629810 | HCID 42629810 | 84% |
Reaction Steps
As described for example 220, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester (120 mg, 0.37 mmol) was converted, using L-prolinol instead of 3-amino-1-propanol, to the title compound (122 mg, 84%) which was obtained as a colourless oil. MS: m/e=394.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877782B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-3c86b7dd2a5b4c6dbe6ceb54cbdcba65 |
| Source note | uspto-grants-2014_11 |