HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-3-m-tolyl-isoxazole-4-carboxylic acid ethyl ester → (5-Methyl-3-(p-tolyl)isoxazol-4-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-3-m-tolyl-isoxazole-4-carboxylic acid ethyl ester | HCID 22309055 | — |
| Reactant | Ethyl 5-methyl-3-(P-tolyl)isoxazole-4-carboxylate | HCID 22309056 | — |
| Product | (5-Methyl-3-(p-tolyl)isoxazol-4-yl)methanol | HCID 28473118 | 38% |
Reaction Steps
As described for example 249d, 5-methyl-3-p-tolyl-isoxazole-4-carboxylic acid ethyl ester (12.6 g, 51.4 mmol) was converted, instead of 5-methyl-3-m-tolyl-isoxazole-4-carboxylic acid ethyl ester, to the title compound (3.95 g, 38%) which was obtained as a white solid. MS: m/e=204.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877782B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-5759b1bb32e1415797a0db453bc87fa3 |
| Source note | uspto-grants-2014_11 |