HCID 25225496, compound → HCID 25226944, compound

HRID 332121Notes

Reaction equation

HRID 332121 reaction equation
[C:1]([C:9]1[O:13][C:12]2[C:14](=[O:24])[C:15]3[C:20]([C:21](=[O:22])[C:11]=2[CH:10]=1)=[CH:19][CH:18]=[C:17](Br)[CH:16]=3)(=[O:8])[C:2]1C=CC=CC=1.C(C1OC2C(=O)C3C(C(=O)C=2C=1)=CC=C([Cl:41])C=3)C>>[C:1]([C:9]1[O:13][C:12]2[C:14](=[O:24])[C:15]3[C:20]([C:21](=[O:22])[C:11]=2[CH:10]=1)=[CH:19][CH:18]=[C:17]([Cl:41])[CH:16]=3)(=[O:8])[CH3:2]

Participants

3

Reactant 2

HCID 25225496HCID 25225496, compoundHCID 25225498HCID 25225498, compound

Product 1

HCID 25226944HCID 25226944, compoundYield 30%

Procedure

The 2-acetyl-7-chloro-4H,9H-naphtho [2,3-b]furan-4,9-dione 3-2 (R1=Cl, R3=CH3, R7=H) was obtained according to the procedure described in example 13 by using 2-ethyl-7-chloro-4H,9H-naphtho[2,3-b]furan-4,9-dione 1-3 (R1=C1, R4=CH3) as starting materials with yield of 30%. 1H NMR (in CDCl3) δ 2.67 (s, 3H), 7.61 (s, 1H), 7.74-7.78 (m, 1H), 8.17-8.23 (m, 2H).

Sources & evidence

ORD record
ord-947d2c3155674a27803bf3a334d87582
Source dataset
uspto-grants-2014_11
Patent number
US08877803B2

Reaction notes

Loading…