HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Difluorobenzenesulfonyl Chloride → 3-[(4-chloro-2-{[(2,4-difluorophenyl)sulfonyl]amino}phenyl)thio]-N,N-dimethylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Difluorobenzenesulfonyl Chloride | HCID 2734273 | — |
| Reactant | 3-((2-amino-4-chlorophenyl)thio)-N,N-dimethylpropanamide | HCID 60961870 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 3-[(4-chloro-2-{[(2,4-difluorophenyl)sulfonyl]amino}phenyl)thio]-N,N-dimethylpropanamide | HCID 67971905 | 72% |
Reaction Steps
Following General Procedure B, the title compound (364 mg, 72%) was prepared from 3-((2-amino-4-chlorophenyl)thio)-N,N-dimethylpropanamide (300 mg, 1.167 mmol) and 2,4-difluorobenzene-1-sulfonyl chloride (248 mg, 1.167 mmol) in pyridine (5 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877804B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-bae577445ba347b3a26ccc691c08f4d2 |
| Source note | uspto-grants-2014_11 |