HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzofuran-2-sulfonyl chloride → N-{5-chloro-2-[(pyrimidin-2-ylmethyl)thio]phenyl}-1-benzofuran-2-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzofuran-2-sulfonyl chloride | HCID 2795172 | — |
| Reactant | 5-Chloro-2-((pyrimidin-2-ylmethyl)thio)aniline | HCID 62698810 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-{5-chloro-2-[(pyrimidin-2-ylmethyl)thio]phenyl}-1-benzofuran-2-sulfonamide | HCID 67972660 | 51% |
Reaction Steps
Following General Procedure B, the title compound (243 mg, 51%) was prepared from 5-chloro-2-((pyrimidin-2-ylmethyl)thio)aniline (280 mg, 1.11 mmol) and benzofuran-2-sulfonyl chloride (240 mg, 1.11 mmol) in pyridine (3 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877804B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-a74d429f010e47f5842dcb96d224d21d |
| Source note | uspto-grants-2014_11 |