4-Chlorobenzenesulfonyl chloride → N-{2-[(3-aminobenzyl)thio]-5-chlorophenyl}-4-chlorobenzenesulfonamide

HRID 332196Notes

Reaction equation

HRID 332196 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[SH:9].Br[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-])=O)[CH:13]=1.[Cl:21][C:22]1[CH:27]=[CH:26][C:25]([S:28](Cl)(=[O:30])=[O:29])=[CH:24][CH:23]=1>>[NH2:18][C:14]1[CH:13]=[C:12]([CH:17]=[CH:16][CH:15]=1)[CH2:11][S:9][C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[NH:1][S:28]([C:25]1[CH:26]=[CH:27][C:22]([Cl:21])=[CH:23][CH:24]=1)(=[O:30])=[O:29]

Participants

4

Reactant 3

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 120002-Amino-4-chlorobenzenethiolHCID 77568Benzene, 1-(bromomethyl)-3-nitro-

Product 1

HCID 57378103N-{2-[(3-aminobenzyl)thio]-5-chlorophenyl}-4-chlorobenzenesulfonamide

Procedure

Following General Procedure A, B, and K, the title compound was prepared from 2-amino-4-chloro-benzenethiol, 1-bromomethyl-3-nitro-benzene, and 4-chloro-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-e32da5a9084c435da1fda6363b6d405c
Source dataset
uspto-grants-2014_11
Patent number
US08877804B2

Reaction notes

Loading…