HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-fluorobenzene-1-sulfonyl chloride → 4-chloro-N-[5-chloro-2-(methylthio)phenyl]-2-fluorobenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-fluorobenzene-1-sulfonyl chloride | HCID 2778860 | — |
| Reactant | 5-Chloro-2-(methylthio)aniline | HCID 2794577 | — |
| Product | 4-chloro-N-[5-chloro-2-(methylthio)phenyl]-2-fluorobenzenesulfonamide | HCID 57378996 | 66.1% |
Reaction Steps
Following General Procedure B, the title compound (380 mg, 66%) was prepared from 5-chloro-2-methylsulfanyl-phenylamine (273 mg, 1.57 mmol) and 4-chloro-2-fluoro-benzenesulfonyl chloride (360 mg, 1.57 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877804B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-ab62ba42ff944e3bb02c922844ec77c2 |
| Source note | uspto-grants-2014_11 |