HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1-Methylcyclopropyl)amine hydrochloride → HCID 57520473, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1-Methylcyclopropyl)amine hydrochloride | HCID 12953687 | — |
| Reactant | 6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid | HCID 66599213 | — |
| Product | HCID 57520473 | HCID 57520473 | 83% |
Reaction Steps
As described for example 8b, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (100 mg, 0.32 mmol) was converted, using 1-methylcyclopropylamine hydrochloride instead of methylamine, to the title compound (97 mg, 83%) which was obtained as a white solid. MS: m/e=362.5 [M−H]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877783B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-7381a9792f3a45b6a6f95127b94d79da |
| Source note | uspto-grants-2014_11 |