(3-((8-(1,3-Dioxolan-2-yl)octyl)oxy)-5-bromophenyl)methanol → HCID 86676900, compound

Participants

Reaction Conditions

Reaction Steps

To a stirred solution of (3-((8-(1,3-dioxolan-2-yl)octyl)oxy)-5-bromophenyl)methanol (1.69 g, 4.36 mmol) in 1,4-dioxane (25 mL), was added magnesium (IV) oxide (1.90 g, 21.9 mmol). The reaction mixture was heated to 100° C. for 16 hours. The suspension was filtered, washed with ethyl acetate, and the filtrate was concentrated under reduced pressure to afford the title compound (1.25 g, 74%).

Provenance & Evidence