Triphenylphosphine → HCID 71093170, compound

Participants

Reaction Conditions

Reaction Steps

To a stirred reaction of 2-(8-(3-(azido(phenyl)methyl)-5-bromophenoxy)octyl)-1,3-dioxolane (1.19 g, 2.45 mmol) in tetrahydrofuran (15 mL) and water (0.3 mL), was added triphenylphosphine (0.71 g, 2.69 mmol). The reaction mixture was heated to 60° C. for 16 hours. The reaction mixture was cooled, concentrated and purified by silica gel chromatography eluting with 0-100% ethyl acetate in iso-hexane to afford impure title compound as a colourless oil (0.77 g, 68%).

Provenance & Evidence