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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 332667Generated: October 30, 2026

3-(8-(1,3-Dioxolan-2-yl)octyloxy)benzaldehyde → (3-((5-(1,3-Dioxolan-2-yl)pentyl)oxy)phenyl)(3-fluorophenyl)methanol

https://huagongshe.com/reaction/332667

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(8-(1,3-Dioxolan-2-yl)octyloxy)benzaldehydeHCID 86676897—
Reactant3-((5-(1,3-Dioxolan-2-yl)pentyl)oxy)benzaldehydeHCID 86676902—
ReactantHCID 178505773HCID 178505773—
Product(3-((5-(1,3-Dioxolan-2-yl)pentyl)oxy)phenyl)(3-fluorophenyl)methanolHCID 71113307—

Reaction Steps

The title compound was prepared as described in Example 10 Step 2 with 3-fluorophenylmagnesium bromide and 3-((5-(1,3-dioxolan-2-yl)pentyl)oxy)benzaldehyde replacing 2-thienylmagnesium bromide and 3-(8-(1,3-dioxolan-2-yl)octyloxy)benzaldehyde respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08877774B2
Source datasetuspto-grants-2014_11
ORD IDord-aa59e145dcc649b7ac39487b32e6c073
Source noteuspto-grants-2014_11