HRID332687

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID552072

2-(3-Chloropropyl)-1,3-dioxolane

C6H11ClO2

结构：CC(C)(C)OC(=O)NC(c1ccccc1)c1cccc(OCC(=O)O)c1

HCID71093126

未命名化合物

结构：BrCCCCCC1OCCO1.[N-]=[N+]=NC(c1ccccc1)c1cccc(OCc2ccc(C(=O)O)cc2)c1

HCID86676909

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)NC(c1ccccc1)c1cccc(OCC(=O)OCCCCCC2OCCO2)c1

HCID71093255

未命名化合物

PROCEDURE

实验过程

The title compound was prepared as described in Example 54 Step 1 with -(3-(((tert-Butoxycarbonyl)amino)(phenyl)methyl)phenoxy)acetic acid and 2-(5-bromopentyl)-1,3-dioxolane 4-((3-(azido(phenyl)methyl)phenoxy)methyl)benzoic acid and 2-(3-chloropropyl)-1,3-dioxolane respectively.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-40a05236085d433691e0d90d1471f7ae
来源数据集: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08877774B2
来源说明: uspto-grants-2014_11

反应 SMILES

[C:1]([O:5][C:6]([NH:8][CH:9]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[C:10]1[CH:11]=[C:12]([CH:18]=[CH:19][CH:20]=1)[O:13][CH2:14][C:15]([OH:17])=[O:16])=[O:7])([CH3:4])([CH3:3])[CH3:2].N(C(C1C=CC=CC=1)C1C=C(C=CC=1)OCC1C=CC(C(O)=O)=CC=1)=[N+]=[N-].Br[CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][CH:60]1[O:64][CH2:63][CH2:62][O:61]1.ClCCCC1OCCO1>>[C:1]([O:5][C:6]([NH:8][CH:9]([C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)[C:10]1[CH:11]=[C:12]([CH:18]=[CH:19][CH:20]=1)[O:13][CH2:14][C:15]([O:17][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][CH:60]1[O:64][CH2:63][CH2:62][O:61]1)=[O:16])=[O:7])([CH3:4])([CH3:2])[CH3:3]