2-(3-Chloropropyl)-1,3-dioxolane → HCID 71093448, compound

HRID 332704Notes

Reaction equation

HRID 332704 reaction equation
[C:1]([O:5][C:6]([NH:8][CH:9]([C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)[C:10]1[CH:11]=[C:12]([CH:24]=[CH:25][CH:26]=1)[O:13][CH2:14][C:15]1[CH:23]=[CH:22][C:18]([C:19]([OH:21])=[O:20])=[CH:17][CH:16]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl[CH2:34][CH2:35][CH2:36][CH:37]1[O:41][CH2:40][CH2:39][O:38]1>>[C:1]([O:5][C:6]([NH:8][CH:9]([C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)[C:10]1[CH:11]=[C:12]([CH:24]=[CH:25][CH:26]=1)[O:13][CH2:14][C:15]1[CH:23]=[CH:22][C:18]([C:19]([O:21][CH2:34][CH2:35][CH2:36][CH:37]2[O:41][CH2:40][CH2:39][O:38]2)=[O:20])=[CH:17][CH:16]=1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 5520722-(3-Chloropropyl)-1,3-dioxolaneHCID 71093158HCID 71093158, compound

Product 1

HCID 71093448HCID 71093448, compound

Procedure

The title compound was prepared from 4-((3-(((tert-butoxycarbonyl)amino)-(phenyl)methyl)phenoxy)methyl)benzoic acid and 2-(3-chloropropyl)-1,3-dioxolane according to the method of Chiral Example 5 Step 1.

Sources & evidence

ORD record
ord-69658d2672a74654830c239efa1b0306
Source dataset
uspto-grants-2014_11
Patent number
US08877774B2

Reaction notes

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