HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Amino-3,3-diethoxypropane → 3-(3-(Phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)propyl 4-((1,3-dioxolan-2-yl)methyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Amino-3,3-diethoxypropane | HCID 521029 | — |
| Reactant | 4-(1,3-Dioxolan-2-ylmethyl)benzoic acid | HCID 24726991 | — |
| Reactant | (R)-Quinuclidin-3-yl((3-(3-hydroxypropoxy)phenyl)(phenyl)methyl)carbamate | HCID 117680437 | — |
| Product | 3-(3-(Phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)propyl 4-((1,3-dioxolan-2-yl)methyl)benzoate | HCID 71093290 | — |
Reaction Steps
The title compound was prepared as described in Chiral Example 11 Step 2 with (R)-quinuclidin-3-yl((3-(3-hydroxypropoxy)phenyl)(phenyl)methyl)carbamate and 4-(1,3-dioxolan-2-ylmethyl)-benzoic acid replacing 4-((3-(phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoic acid and 1-amino-3,3-diethoxypropane, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877774B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-524c5b4df8eb41febab644e96cd03f8e |
| Source note | uspto-grants-2014_11 |