Hydrochloric Acid → 3-(1,3-Dioxolan-2-yl)propyl 4-(5-((3-(amino(phenyl)methyl)phenoxy)methyl)-1,2,4-oxadiazol-3-yl)benzoate hydrochloride

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Reaction Steps

Hydrogen chloride in dioxan (4.0 M, 5 mL, 24 mmol) was added to 3-(1,3-dioxolan-2-yl)propyl 4-(5-((3-(((tert-butoxycarbonyl)amino)(phenyl)methyl)-phenoxy)methyl)-1,2,4-oxadiazol-3-yl)benzoate (0.237 g, 0.41 mmol), and the resultant solution was stirred at ambient temperature for 2 hours. The solvent was evaporated at reduced pressure to afford the title compound (0.212 g, 100%).

Provenance & Evidence