HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → 2-chloro-N-(4-phenoxyphenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | (4-Aminophenoxy)benzene | HCID 8764 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-chloro-N-(4-phenoxyphenyl)acetamide | HCID 736969 | — |
Reaction Steps
To 3.55 g of 4-phenoxyaniline in 40 ml of methylene chloride containing 2.9 ml of triethylamine is added 1.6 ml of chloroacetyl choride in 20 ml of methylene chloride. After two hours at room temperature, the mixture is extracted with water to yield 2.74 g of N-(4-phenoxyphenyl)-2-chloro-acetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877940B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-cf943c4f991942ba81ff0554b785c4d3 |
| Source note | uspto-grants-2014_11 |