N-BOC-ethylenediamine → HCID 67121345, compound

Participants

Reaction Steps

A solution of N-{4-[(2,5-dioxoazolidinyloxy)carbonylamino]phenyl}(fluoren-9-ylmethoxy)carboxamide (16.10 g, 34.15 mmol, 1.0 eq) in H2O/CH3CN (1/1, v/v, 360 mL) is reacted at room temperature with NaHCO3 (2.86 g, 34.15 mmol, 1.0 eq) and N—BOC-ethylenediamine (5.47 g, 34.15 mmol, 1.0 eq). After stirring overnight at room temperature, the reaction mixture is filtered to afford 16.36 g of the expected crude product as a white solid.

Provenance & Evidence