2-Fluoro-4-iodoaniline → HCID 57773689, compound

HRID 333120Notes

Reaction equation

HRID 333120 reaction equation
[N:1]([C:4]1[CH:5]=[C:6]([S:10]([NH2:13])(=[O:12])=[O:11])[CH:7]=[CH:8][CH:9]=1)=[C:2]=[S:3].[F:14][C:15]1[CH:21]=[C:20]([I:22])[CH:19]=[CH:18][C:16]=1[NH2:17]>>[F:14][C:15]1[CH:21]=[C:20]([I:22])[CH:19]=[CH:18][C:16]=1[NH:17][C:2](=[S:3])[NH:1][C:4]1[CH:5]=[C:6]([S:10]([NH2:13])(=[O:11])=[O:12])[CH:7]=[CH:8][CH:9]=1

Participants

3

Reactant 2

HCID 1856942-Fluoro-4-iodoanilineHCID 100361773-isothiocyanatobenzenesulfonamide

Product 1

HCID 57773689HCID 57773689, compound

Procedure

The subject compound was prepared utilizing the procedure described above from 3-isothiocyanatobenzenesulfonamide and 2-fluoro-4-iodoaniline. 1H NMR (400 MHz, DMSO-d6) δ 10.19 (s, 1H), 9.67 (s, 1H), 7.96 (m, 1H), 7.70 (m, 2H), 7.58-7.49 (m, 3H), 7.38 (bs, 3H); (M+H)+ (452).

Workup

  1. customThe subject compound was prepared

Sources & evidence

ORD record
ord-391920e83f8347c1887650f5e39275b1
Source dataset
uspto-grants-2014_11
Patent number
US08877970B2

Reaction notes

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