Hydrochloric Acid → HCID 68630202, compound

Participants

Reaction Steps

To a round bottom flask containing N-(5-sulfamoyl-2,3-dihydro-1H-inden-1-yl)acetamide (1 g, 3.9 mmol) was added 12N hydrochloric acid (100 mL) and the reaction was heated to a reflux for 2 days. The reaction was cooled and concentrated to afford MIP-1153 (785 mg, 96%) as a light tan solid. 1H NMR (400 MHz, DMSO-d6) δ 7.46-7.20 (m, 3H), 3.78 (br, 6H), 3.21-1.97 (m, 4H); (M+H)+ (212).

Provenance & Evidence