Ethyl formate → HCID 72473811, compound

Participants

Reaction Steps

50 g (184.4 mmol) of 1-[1-(3,4-Dichloro-phenyl)-cyclohexyl]-ethylamine was dissolved in 1 L of ethylformate and left to stir under an N2 atmosphere for 24 h before removing all volatiles under reduced pressure. The resulting solid was filtered through a plug of SiO2 (using CH2Cl2/MeOH (20:1) as the eluent) to afford 51.32 g (93%) of the title compound after the removal of all volatiles. This material was used in the subsequent step without further purification.

Provenance & Evidence