Ethanol → Piperidin-1-yl-(1-trityl-1H-imidazol-4-yl-methylene)amine

Participants

Reaction Conditions

Reaction Steps

To a solution containing 342 mg (1.01 mmol) of 1-trityl-1H-imidazole-4-carbaldehyde and 100 mg (1.0 mmol) of piperidin-1-ylamine are added 3.5 mL of ethanol and 1.5 mL of dichloromethane. The reaction medium is heated at 80° C. for 1 hour. The solvents are evaporated off and 450 mg of a powder are obtained and used in the following step without further purification.

Provenance & Evidence