HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-nitro-N-phenylpyridin-2-amine → 2-N-phenylpyridine-2,3-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-nitro-N-phenylpyridin-2-amine | HCID 611799 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-N-phenylpyridine-2,3-diamine | HCID 10679091 | 80% |
Reaction Steps
3-nitro-N-phenylpyridin-2-amine (29 g, 135 mmol) and palladium on carbon (10 wt %, 3 g) in ethanol (200 mL) were hydrogenated on a Parr hydrogenator at 45 psi for 8 h. The catalyst was filtered. The solution was concentrated to give N2-phenylpyridine-2,3-diamine (20 g, 80% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883322B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-d0eb23e386224da1a9b9e883f05aaadf |
| Source note | uspto-grants-2014_11 |