反应详情

10% palladium on carbon (10%; 0.50 g, 0.47 mmol) was added to a Parr hydrogenation bottle. The bottle was purged with nitrogen. Next, N-(dibenzo[b,d]furan-4-yl)-3-nitropyridin-2-amine (3.8 g, 12.45 mmol) and 200 mL ethanol were added. The reaction mixture was hydrogenated overnight using a Parr hydrogenator. The reaction mixture was filtered through Celite® and the Celite® washed with dichloromethane and ethyl acetate. The filtrate was evaporated leaving a dark brown solid, which was not purified (3.32 g, 97%).

1. customThe bottle was purged with nitrogen
2. filtrationThe reaction mixture was filtered through Celite®
3. washthe Celite® washed with dichloromethane and ethyl acetate
4. customThe filtrate was evaporated
5. customleaving a dark brown solid, which
6. customwas not purified (3.32 g, 97%)