1-Acetoxy-2-bromoethane → HCID 57421233, compound

HRID 333782Notes

Reaction equation

HRID 333782 reaction equation
[C:1]([O:4][CH2:5][CH2:6]Br)(=[O:3])[CH3:2].[Cl:8][C:9]1[CH:10]=[C:11]([OH:30])[CH:12]=[CH:13][C:14]=1[CH:15]([CH3:29])[C:16]([OH:28])([C:21]1[CH:26]=[N:25][C:24]([CH3:27])=[CH:23][N:22]=1)[C:17]([F:20])([F:19])[F:18]>>[Cl:8][C:9]1[CH:10]=[C:11]([CH:12]=[CH:13][C:14]=1[CH:15]([CH3:29])[C:16]([OH:28])([C:21]1[CH:26]=[N:25][C:24]([CH3:27])=[CH:23][N:22]=1)[C:17]([F:19])([F:18])[F:20])[O:30][CH2:6][CH2:5][O:4][C:1](=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 135641-Acetoxy-2-bromoethaneHCID 574212313-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(5-methyl-pyrazin-2-yl)-propyl]-phenol

Product 1

HCID 57421233HCID 57421233, compound

Procedure

The title compound was prepared in analogy to Example 74 from 2-bromoethyl acetate and 3-chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(5-methyl-pyrazin-2-yl)-propyl]-phenol (Example 72). MS (m/e)=433.1 (MH+).

Sources & evidence

ORD record
ord-ad9e9f3636da4cdb9e5b40c7f9b9b350
Source dataset
uspto-grants-2014_11
Patent number
US08883786B2

Reaction notes

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