HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromoacetamide → 2-{4-[2-(2,4-Dichloro-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-pyridin-2-yloxy}-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromoacetamide | HCID 69632 | — |
| Reactant | HCID 57421256 | HCID 57421256 | — |
| Product | 2-{4-[2-(2,4-Dichloro-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-pyridin-2-yloxy}-acetamide | HCID 25254608 | — |
Reaction Steps
The title compound was prepared in analogy to Example 120 from 4-[2-(2,4-dichloro-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1H-pyridin-2-one (Example 119, 100 mg) and 2-bromo-acetamide (45 mg). MS (m/e)=423.1 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883786B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-6ed5d89540594da29e73d4ffbdb80709 |
| Source note | uspto-grants-2014_11 |