化工社化工社 化学情報印刷レポート · 研究参考用
Methyl iodide → 6-Nitro-o-anisidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl iodide | HCID 6328 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | 2-Amino-3-Nitrophenol | HCID 4115495 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 6-Nitro-o-anisidine | HCID 85491 | — |
反応手順
85% potassium hydroxide solution (11.7 g, 0.179 mol) is added to a solution of 25 g (0.162 mol) 2-amino-3-nitro-phenol in 200 mL DMF. Then 11.1 mL (0.178 mol) iodomethane are added dropwise and the mixture is stirred overnight at ambient temperature. The reaction mixture is poured onto ice and stirred for one hour. The precipitated product is filtered off, washed with water and dried.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07429583B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-256aa94f9e5847479f45c40f7a09c03e |
| 出典メモ | uspto-grants-2008_09 |