HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-[2-(2,4-Dichloro-phenyl)-acryloyl]-1H-pyridin-2-one → 5-[2-(2,4-Dichloro-phenyl)-propionyl]-1H-pyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-[2-(2,4-Dichloro-phenyl)-acryloyl]-1H-pyridin-2-one | HCID 57421353 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 5-[2-(2,4-Dichloro-phenyl)-propionyl]-1H-pyridin-2-one | HCID 57421354 | 27.5% |
Reaction Steps
5-[2-(2,4-Dichloro-phenyl)-acryloyl]-1H-pyridin-2-one (840 mg) was hydrogenated in EtOAc using 5% Pd/Alox as a catalyst to give the title compound (233 mg) as a light brown solid. MS (m/e, ISP neg. ion)=293.8 [M−H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883786B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-83327e8517654c939be08d37f3631b79 |
| Source note | uspto-grants-2014_11 |