N,N-Dimethyl-1,3-propanediamine → 4-(3-(Dimethylamino)propylamino)-3-(trifluoromethylsulfonyl)benzenesulfonamide

HRID 333876Notes

Reaction equation

HRID 333876 reaction equation
FC1C=CC(S(N)(=O)=O)=CC=1[N+]([O-])=O.[CH3:15][N:16]([CH3:21])[CH2:17][CH2:18][CH2:19][NH2:20].F[C:23]1[CH:28]=[CH:27][C:26]([S:29]([NH2:32])(=[O:31])=[O:30])=[CH:25][C:24]=1[S:33]([C:36]([F:39])([F:38])[F:37])(=[O:35])=[O:34]>>[CH3:15][N:16]([CH3:21])[CH2:17][CH2:18][CH2:19][NH:20][C:23]1[CH:28]=[CH:27][C:26]([S:29]([NH2:32])(=[O:31])=[O:30])=[CH:25][C:24]=1[S:33]([C:36]([F:37])([F:39])[F:38])(=[O:35])=[O:34]

Participants

4

Reactant 3

HCID 7993N,N-Dimethyl-1,3-propanediamineHCID 167824874-Fluoro-3-nitrobenzenesulfonamideHCID 250584524-Fluoro-3-((trifluoromethyl)sulfonyl)benzenesulfonamide

Product 1

HCID 672271174-(3-(Dimethylamino)propylamino)-3-(trifluoromethylsulfonyl)benzenesulfonamide

Procedure

The title compound was prepared by following the procedure described in Example 10C, replacing Example 10B and 4-fluoro-3-nitrobenzenesulfonamide with N′,N′-dimethylpropane-1,3-diamine and 4-fluoro-3-(trifluoromethylsulfonyl)benzenesulfonamide, respectively.

Sources & evidence

ORD record
ord-c5f6df1f22b3481c85798395b7244a44
Source dataset
uspto-grants-2014_11
Patent number
US08883784B2

Reaction notes

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