HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 89845382, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | HCID 57389812 | HCID 57389812 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 89845382 | HCID 89845382 | 75.4% |
Reaction Steps
The compound of Example 23 (54 mg) was N-methylated by the action of paraformaldehyde (50 mg) and sodium cyanoborohydride (63 mg) in ethanol to obtain a crude product. Subsequently, 21 mg of the title compound was obtained as a gray solid (35%) with reference to the method of Step 3 of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883792B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-957e6ddf0d384d1eac5197385144b61e |
| Source note | uspto-grants-2014_11 |