1-(4-Amino-4-methyl-pentyl)-1,3-dihydro-benzimidazol-2-one → HCID 59796461, compound

HRID 33401Notes

Reaction equation

HRID 33401 reaction equation
C([O:8][C:9]1[CH:10]=[C:11]([CH:20]([OH:26])[CH:21](OCC)O)[C:12]2[O:17][CH2:16][C:15](=[O:18])[NH:14][C:13]=2[CH:19]=1)C1C=CC=CC=1.[NH2:27][C:28]([CH3:43])([CH3:42])[CH2:29][CH2:30][CH2:31][N:32]1[C:36]2[CH:37]=[CH:38][CH:39]=[CH:40][C:35]=2[NH:34][C:33]1=[O:41]>>[CH3:43][C:28]([NH:27][CH2:21][CH:20]([C:11]1[C:12]2[O:17][CH2:16][C:15](=[O:18])[NH:14][C:13]=2[CH:19]=[C:9]([OH:8])[CH:10]=1)[OH:26])([CH3:42])[CH2:29][CH2:30][CH2:31][N:32]1[C:36]2[CH:37]=[CH:38][CH:39]=[CH:40][C:35]=2[NH:34][C:33]1=[O:41]

Participants

3

Reactant 2

HCID 131747201-(4-Amino-4-methyl-pentyl)-1,3-dihydro-benzimidazol-2-oneHCID 671880306-benzyloxy-8-(2-ethoxy-1,2-dihydroxy-ethyl)-4H-benzo[1,4]oxazin-3-one

Product 1

HCID 59796461HCID 59796461, compound

Procedure

Prepared according to general method 2 from 357 mg (1 mmol) 6-benzyloxy-8-(2-ethoxy-1,2-dihydroxy-ethyl)-4H-benzo[1,4]oxazin-3-one and 233 mg (1 mmol) 1-(4-amino-4-methyl-pentyl)-1,3-dihydro-benzimidazol-2-one. Yield: 192 mg (44%); mass spectroscopy: [M+H]+=441.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-ef5638ebbd08445cb4190242fd19c16c
Source dataset
uspto-grants-2008_09
Patent number
US07429583B2

Reaction notes

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