3-Fluoroaniline → 2-(3-Fluoro-phenyl)-2H-tetrazole-5-carboxylic acid

HRID 334030Notes

Reaction equation

HRID 334030 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([NH2:8])[CH:5]=[CH:6][CH:7]=1.ClC1C=C([N:16]2N=[N:19][C:18]([C:21]([OH:23])=[O:22])=[N:17]2)C=CC=1>>[F:1][C:2]1[CH:3]=[C:4]([N:8]2[N:16]=[N:17][C:18]([C:21]([OH:23])=[O:22])=[N:19]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 97423-FluoroanilineHCID 664909762-(3-Chloro-phenyl)-2H-tetrazole-5-carboxylic acid

Product 1

HCID 822836232-(3-Fluoro-phenyl)-2H-tetrazole-5-carboxylic acid

Procedure

This intermediate was prepared from 3-fluoro-phenylamine in four steps according to the preparation of 2-(3-chloro-phenyl)-2H-tetrazole-5-carboxylic acid.

Sources & evidence

ORD record
ord-a2e9e0d712bd4ebc9f39457c7dfddd3a
Source dataset
uspto-grants-2014_11
Patent number
US08883789B2

Reaction notes

Loading…