HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Boc-3,3-dimethylpiperazine → [2-(3-Chloro-phenyl)-2H-tetrazol-5-yl]-(2,2-dimethyl-piperazin-1-yl)methanone trifluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Boc-3,3-dimethylpiperazine | HCID 22710387 | — |
| Reactant | 2-(3-Chloro-phenyl)-2H-tetrazole-5-carboxylic acid | HCID 66490976 | — |
| Reactant | (2,2-dimethyl-piperazin-1-yl)-(1-phenyl-1-H-[1,2,4]triazol-3-yl)-methanone trifluoroacetate | HCID 86688259 | — |
| Product | [2-(3-Chloro-phenyl)-2H-tetrazol-5-yl]-(2,2-dimethyl-piperazin-1-yl)methanone trifluoroacetate | HCID 86688273 | — |
Reaction Steps
This intermediate was prepared from 2-(3-chloro-phenyl)-2H-tetrazole-5-carboxylic acid and 3,3-dimethyl-piperazine-1-carboxylic acid tert-butyl ester in two steps according to the preparation of (2,2-dimethyl-piperazin-1-yl)-(1-phenyl-1-H-[1,2,4]-triazol-3-yl)-methanone trifluoroacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883789B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-886e7140426546ea97800ccc5fe3a76b |
| Source note | uspto-grants-2014_11 |