1,3-Dichloro-6,7-dimethoxyisoquinoline → HCID 86688286, compound

HRID 334062Notes

Reaction equation

HRID 334062 reaction equation
ClC1C2C(=CC(OC)=[C:9]([O:12]C)C=2)C=C(Cl)N=1.[CH3:17][O:18][C:19]1[C:28]2[C:23](=[CH:24][C:25]([O:29][CH3:30])=[CH:26][CH:27]=2)[CH:22]=[C:21]([C:31]([OH:33])=[O:32])[N:20]=1>>[CH3:17][O:18][C:19]1[C:28]2[C:23](=[CH:24][C:25]([O:29][CH3:30])=[C:26]([O:12][CH3:9])[CH:27]=2)[CH:22]=[C:21]([C:31]([OH:33])=[O:32])[N:20]=1

Participants

3

Reactant 2

HCID 534009131,3-Dichloro-6,7-dimethoxyisoquinolineHCID 84696473HCID 84696473, compound

Product 1

HCID 86688286HCID 86688286, compound

Procedure

This intermediate was prepared from 1,3-dichloro-6,7-dimethoxy-isoquinoline in three steps according to the preparation of 1,6-dimethoxy-isoquinoline-3-carboxylic acid.

Sources & evidence

ORD record
ord-83f44c87604441fe937cd7b1d9d4fce2
Source dataset
uspto-grants-2014_11
Patent number
US08883789B2

Reaction notes

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