HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 86688321, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | 1-(3-Chlorophenyl)-1H-1,2,4-triazole-3-carboxylic acid | HCID 71301927 | — |
| Reactant | HCID 86688322 | HCID 86688322 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86688321 | HCID 86688321 | — |
Reaction Steps
A mixture of 71 mg (0.30 mmol) (6-methoxy-pyridin-2-yl)-((R)-3-methyl-piperazin-1-yl)-methanone, 67 mg (0.30 mmol) 1-(3-chloro-phenyl)-1H-[1,2,4]-triazole-3-carboxylic acid, 0.11 g (0.33 mmol) TBTU and 77 μL (0.45 mmol) DIPEA in 1.5 mL DMF was stirred at RT for 12 h. The reaction mixture was purified by HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883789B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-9925c28e993f485d86158e77a4811646 |
| Source note | uspto-grants-2014_11 |