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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 334296Generated: October 30, 2026

1-(4-Fluorophenyl)piperazine → HCID 71678507, compound

https://huagongshe.com/reaction/334296

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Fluorophenyl)piperazineHCID 75260—
Reactant3-PhenylbenzaldehydeHCID 121053—
ReactantSodium triacetoxyborohydrideHCID 5049666—
Reactant1-(Biphenyl-2-ylmethyl)-4-phenylpiperazineHCID 71602523—
ProductHCID 71678507HCID 71678507—

Reaction Steps

74.7 mg of the target compound (0.22 mmol, 26.8%) was obtained using 1-(4-fluorophenyl)piperazine (296 mg, 1.64 mmol), biphenyl-3-carbaldehyde (150 mg, 0.82 mmol) and NaBH(OAc)3 (529 mg, 2.46 mmol) according to the synthesis method of Compound 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08883796B2
Source datasetuspto-grants-2014_11
ORD IDord-2121fabcc3994416a032f37e8ae18d94
Source noteuspto-grants-2014_11