反应详情

To a solution of 4-(4-chlorophenyl)-2-methylthiopyrimidine (1.1 g, 4.65 mmol) in acetone (30 ml) and water (10 ml) was added oxone (7.14 g, 11.62 mmol). The reaction mixture was stirred for 18 hours then diluted with water and extracted into dichloromethane. The extracts were dried over magnesium sulfate, filtered and concentrated to provide a white solid: EI-MS (m/z) 269 [M+1]+.

1. extractionextracted into dichloromethane
2. dry with materialThe extracts were dried over magnesium sulfate
3. filtrationfiltered
4. concentrationconcentrated
5. customto provide a white solid