HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Iodopyridine → HCID 11557859, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Iodopyridine | HCID 221126 | — |
| Reactant | HCID 86086747 | HCID 86086747 | — |
| Product | HCID 11557859 | HCID 11557859 | 29% |
Reaction Steps
The title compound was prepared in accordance with the general method of Example 1, from 2-iodopyridine (100 mg, 0.49 mmol) and 2-(but-3-ynyl)oxazolo[4,5-b]pyridine (100 mg, 0.58 mmol) at room temperature. The crude residue was purified by flash chromatography (DCM/MeOH 99:1 to 98:2) to yield 35 mg (0.14 mmol, 29%) of 2-(4-(pyridin-2-yl)but-3-ynyl)oxazolo[4,5-b]pyridine as a brown semi-solid with a purity of 86%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883826B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-0992f139d6b2437bbc2d8decb8cb3885 |
| Source note | uspto-grants-2014_11 |