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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 334577Generated: October 30, 2026

2-Iodopyridine → HCID 11557859, compound

https://huagongshe.com/reaction/334577

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-IodopyridineHCID 221126—
ReactantHCID 86086747HCID 86086747—
ProductHCID 11557859HCID 1155785929%

Reaction Steps

The title compound was prepared in accordance with the general method of Example 1, from 2-iodopyridine (100 mg, 0.49 mmol) and 2-(but-3-ynyl)oxazolo[4,5-b]pyridine (100 mg, 0.58 mmol) at room temperature. The crude residue was purified by flash chromatography (DCM/MeOH 99:1 to 98:2) to yield 35 mg (0.14 mmol, 29%) of 2-(4-(pyridin-2-yl)but-3-ynyl)oxazolo[4,5-b]pyridine as a brown semi-solid with a purity of 86%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08883826B2
Source datasetuspto-grants-2014_11
ORD IDord-0992f139d6b2437bbc2d8decb8cb3885
Source noteuspto-grants-2014_11