HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopyridine → HCID 11687790, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopyridine | HCID 7973 | — |
| Reactant | HCID 86086870 | HCID 86086870 | — |
| Product | HCID 11687790 | HCID 11687790 | 10% |
Reaction Steps
The title compound was prepared in accordance with the general method of Example 1, from 2-bromopyridine (220 mg, 1.39 mmol) and 2-but-3-ynyl-5-fluoro-benzo[d]thiazole (286 mg, 1.39 mmol). The crude residue was purified by flash chromatography (DCM/MeOH 99:1 to 98:2) to yield 38 mg (0.13 mmol, 10%) of 5-fluoro-2-(4-(pyridin-2-yl)but-3-ynyl)benzo[d]thiazole as an orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883826B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-2f94282550f44183bdb5781417fa26ab |
| Source note | uspto-grants-2014_11 |