HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopyridine → 2-(4-(pyridin-2-yl)but-3-ynyl)-2H-benzo[d][1,2,3]triazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopyridine | HCID 7973 | — |
| Reactant | 2-but-3-ynyl-2H-benzo[d][1,2,3]triazole | HCID 57691791 | — |
| Product | 2-(4-(pyridin-2-yl)but-3-ynyl)-2H-benzo[d][1,2,3]triazole | HCID 66598220 | 62.5% |
Reaction Steps
The title compound was prepared in accordance with the general method of Example 1, from 2-bromopyridine (92 mg, 0.58 mmol) and 2-(but-3-ynyl)-2H-benzo[d][1,2,3]triazole (100 mg, 0.58 mmol). Reaction time: 3 hours. The crude residue was purified by flash chromatography (DCM/MeOH 99:1) to yield 90 mg of 2-(4-(pyridin-2-yl)but-3-ynyl)-2H-benzo[d][1,2,3]triazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883826B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-cc41889750924edfbe1b1d765860beef |
| Source note | uspto-grants-2014_11 |