HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-6-(fluoromethyl)pyridine → HCID 66597937, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-6-(fluoromethyl)pyridine | HCID 10241610 | — |
| Reactant | HCID 57691784 | HCID 57691784 | — |
| Product | HCID 66597937 | HCID 66597937 | 17% |
Reaction Steps
The title compound was prepared in accordance with the general method of Example 108(C), from 2-bromo-6-(fluoromethyl)-pyridine (204 mg, 1.07 mmol) and 2-but-3-ynyl-2H-indazole (183 mg, 1.07 mmol). The crude residue was purified by flash chromatography (cyclohexane/AcOEt 3:2) to yield 50 mg (0.18 mmol, 17%) of 2-(4-(6-(fluoromethyl)pyridin-2-yl)but-3-ynyl)-2H-indazole as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883826B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-6c2457055c4846d6883d9eea64a45af5 |
| Source note | uspto-grants-2014_11 |