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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 334795Generated: October 29, 2026

Benzoyl Peroxide → Methyl 2-(bromomethyl)benzoate

https://huagongshe.com/reaction/334795

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl PeroxideHCID 7187—
ReactantMethyl o-toluateHCID 33094—
ReactantN-bromobutanimideHCID 67184—
ProductMethyl 2-(bromomethyl)benzoateHCID 273481392.2%

Reaction Steps

A solution of methyl-2-methylbenzoate (250 mg, 1.66 mmol), NBS (296 mg, 1.66 mmol) and dibenzoylperoxide (403 mg, 1.66 mmol) was stirred under reflux for one day. After purification by flash chromatography, 350 mg (1.53 mmol, 92%) of methyl-2-(bromomethyl)benzoate were obtained as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08883826B2
Source datasetuspto-grants-2014_11
ORD IDord-3ded2dc6b6814f7facc5a440b9ebfa7e
Source noteuspto-grants-2014_11