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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 33488생성일: 2026년 10월 25일

Water → 1-[2-(4-Allyloxy-benzyloxy)-ethyl]-1H-[1,2,3]triazole

https://huagongshe.com/reaction/33488

반응식

참여 물질

역할이름HCID투입량
반응물WaterHCID 962—
반응물Sodium hydrideHCID 24758—
반응물2-(1H-1,2,3-triazol-1-yl)ethan-1-olHCID 9989237—
반응물1-Allyloxy-4-chloromethyl-benzeneHCID 12347936—
용매DimethylformamideHCID 6228—
생성물1-[2-(4-Allyloxy-benzyloxy)-ethyl]-1H-[1,2,3]triazoleHCID 23614530—

반응 단계

197 mg (8.21 mmol) 95% sodium hydride were given at −50° C. to a solution of 1.00 g (5.47 mmol) 1-allyloxy-4-chloromethyl-benzene and 619 mg (5.47 mmol) 2-(1H-[1,2,3]-triazol-1-yl)-ethanol in 9.0 ml N,N-dimethylformamide (DMF). The mixture was allowed to warm slowly to room temperature (r.t.), stirred overnight and 10 ml water was added. The formed oil was collected with 10 ml dichloromethane, the aqueous phase extracted with 10 ml dichloromethane and the combined organic phases dried over Na2SO4.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07429605B2
출처 데이터셋uspto-grants-2008_09
ORD IDord-5bb210cf415341438fbb5281da5cc019
출처 메모uspto-grants-2008_09