Ammonia → HCID 43090064, compound

HRID 335003Notes

Reaction equation

HRID 335003 reaction equation
C([O:3][C:4](=O)[CH2:5][CH2:6][NH:7][C:8]1[CH:13]=[C:12]([CH3:14])[CH:11]=[C:10]([CH3:15])[CH:9]=1)C.[NH3:17]>CO>[CH3:15][C:10]1[CH:9]=[C:8]([NH:7][CH2:6][CH2:5][C:4]([NH2:17])=[O:3])[CH:13]=[C:12]([CH3:14])[CH:11]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 23052938HCID 23052938, compound

Product 1

HCID 43090064HCID 43090064, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

3-(3,5-dimethyl-phenylamino)-propionic acid ethyl ester (0.0026 mol) in a 7N solution of NH3 in CH3OH was stirred at 80° C. in a sealed vessel. The reaction was cooled down to room temperature and the solvent was evaporated until dryness, yielding 0.5 g of 3-(3,5-dimethyl-phenylamino)-propionamide (100%).

Workup

  1. customthe solvent was evaporated until dryness

Sources & evidence

ORD record
ord-920b3102c2f940a79222133846a755d1
Source dataset
uspto-grants-2014_11
Patent number
US08883837B2

Reaction notes

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