HCID 54755721, compound → HCID 71280872, compound

Participants

Reaction Steps

To a solution of N-[(1S,2S)-2-hydroxycyclohexyl]-1-methoxy-4-[(6-vinylpyridin-3-yl)methyl]-2-naphthamide (0.050 g, 0.12 mmol) in 5 mL of methanol was added palladium on carbon (0.013 mg, 0.12 mmol). The mixture was placed under an atmosphere of hydrogen (1 atm) for 15 hours and was then filtered through a pad of Celite, which was washed with MeOH. The filtrate was concentrated in vacuo to provide the title compound that gave a proton NMR spectra consistent with theory and a mass ion (ES+) of 388.1657 for [M+H]+ [Calculated for C23H22N3O3, [M+H]+=388.1656].

Provenance & Evidence