HuagongsheHuagongshe Chemistry Print Report · For research reference only
o-Chlorothiophenol → N-(5-(2-chlorophenylthio)-3-phenoxypyridin-2-yl)-4-methylthiazol-2-amine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | o-Chlorothiophenol | HCID 80599 | — |
| Reactant | 5-Bromo-N-(4-methylthiazol-2-yl)-3-phenoxypyridin-2-amine | HCID 24765543 | — |
| Product | N-(5-(2-chlorophenylthio)-3-phenoxypyridin-2-yl)-4-methylthiazol-2-amine hydrochloride | HCID 24764794 | — |
Reaction Steps
Prepared according to the method of Example 13, using 5-bromo-N-(4-methylthiazol-2-yl)-3-phenoxypyridin-2-amine and 2-chlorobenzenethiol. 1H NMR (d6-DMSO) δ 8.26 (d, 1H), 7.49 (dd, 1H), 7.42 (t, 2H), 7.29 (d, 1H), 7.27-7.12 (m, 4H), 6.96 (dd, 1H), 6.80 (s, 1H), 2.30 (s, 3H); Mass spectrum (esi) m/z=426.4 (M+H—HCl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883828B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-2acc04011a404e05a411bd82ed6900bb |
| Source note | uspto-grants-2014_11 |