Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 1-(5-Bromo-3-(4-fluorophenoxy)pyridin-2-yl)thiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 1-Benzoyl-3-(5-bromo-3-(4-fluorophenoxy)pyridin-2-yl)thiourea | HCID 86631484 | — |
| 생성물 | 1-(5-Bromo-3-(4-fluorophenoxy)pyridin-2-yl)thiourea | HCID 86631485 | 84.3% |
반응 단계
Following the procedure in Example 7, Step D, 1-benzoyl-3-(5-bromo-3-(4-fluorophenoxy)pyridin-2-yl)thiourea (1150 mg, 2.58 mmol) and 3M sodium hydroxide (1.7 mL, 5.1 mmol) provided 1-(5-bromo-3-(4-fluorophenoxy)pyridin-2-yl)thiourea (743 mg, 84.3% yield) as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08883828B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-1157f825e36a40219bfa4188b114871f |
| 출처 메모 | uspto-grants-2014_11 |