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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 335328생성일: 2026년 10월 25일

3-amino-N-benzyl-4-fluorobenzamide → N-(5-(Benzylcarbamoyl)-2-fluorophenyl)-6-iodoimidazo[1,2-a]pyridine-3-carboxamide

https://huagongshe.com/reaction/335328

반응식

참여 물질

역할이름HCID투입량
반응물3-amino-N-benzyl-4-fluorobenzamideHCID 39348132—
반응물6-Bromo-N-(2-methyl-5-(2-(4-methylpiperazin-1-yl)benzylcarbamoyl)phenyl)pyrazolo[1,5-a]pyridine-3-carboxamideHCID 71283253—
반응물6-Iodoimidazo[1,2-a]pyridine-3-carboxylic acidHCID 71283348—
생성물N-(5-(Benzylcarbamoyl)-2-fluorophenyl)-6-iodoimidazo[1,2-a]pyridine-3-carboxamideHCID 71283185—

반응 단계

The title compound was prepared from 6-iodoimidazo[1,2-a]pyridine-3-carboxylic acid (step 1) and 3-amino-N-benzyl-4-fluorobenzamide (step 2) analogously 6-bromo-N-(2-methyl-5-(2-(4-methylpiperazin-1-yl)benzylcarbamoyl)phenyl)pyrazolo[1,5-a]pyridine-3-carboxamide (Intermediate 4A);

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08883819B2
출처 데이터셋uspto-grants-2014_11
ORD IDord-9f4617de7a654806be70b199fb7e05a1
출처 메모uspto-grants-2014_11