HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Thioglycolate → Methyl 1,3-dioxa-5-thia-s-indacene-6-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Thioglycolate | HCID 16907 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1,3-Benzodioxole-5-carboxaldehyde, 6-bromo- | HCID 95062 | — |
| Product | Methyl 1,3-dioxa-5-thia-s-indacene-6-carboxylate | HCID 11746624 | — |
Reaction Steps
Using 3.0 g (13.1 mmol) of 6-bromopiperonal, 0.79 g (19.7 mmol) of sodium hydride (60% pure) and 1.53 g (14.4 mmol) of methyl mercaptoacetate, 732 mg (18.5% of theory) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08884017B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-4699895698a54beeb68d51851ddc4bd2 |
| Source note | uspto-grants-2014_11 |