HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Dimethoxypropane → HCID 66849166, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Dimethoxypropane | HCID 6495 | — |
| Reactant | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| Reactant | HCID 66848946 | HCID 66848946 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 66849166 | HCID 66849166 | — |
Reaction Steps
2,2-Dimethoxypropane and pyridinium p-toluenesulfonate are added to a solution of (S)-3-(1-iodocyclopropyl)propane-1,2-diol dissolved in dichloromethane and the mixture stirred at room temperature for 2 hours. Solvents are removed under reduced pressure and the crude product purified by flash chromatography using ethyl acetate/hexane (1:10) eluant.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08884058B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-3bdaf65d599845a28de6d81838042320 |
| Source note | uspto-grants-2014_11 |