HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → [1-(2-Amino-oxazol-4-yl)-naphthalen-2-yloxy]-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Reactant | 1-(2-Amino-oxazol-4-yl)-naphthalen-2-ol | HCID 59796845 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | [1-(2-Amino-oxazol-4-yl)-naphthalen-2-yloxy]-acetic acid methyl ester | HCID 59796850 | — |
Reaction Steps
1-(2-Amino-oxazol-4-yl)-naphthalen-2-ol (22, 190 mg) was dissolved in N,N-dimethylformamide and then sodium hydride (34 mg) was added in one portion to give a dark orange solution. Methyl bromoacetate (88 μL) was then added and the mixture was stirred at room temperature for 18 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07429607B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-54b0fa1c516745c6ad611f2fff98835f |
| Source note | uspto-grants-2008_09 |